Rapid molecular diagnostics, particularly using AI-LAMP technology, are crucial for combating antimicrobial resistance (AMR) and infectious diseases by enabling fast, accurate, and decentralized testing.
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Thank you for the introduction and thank
you for giving me the opportunity to
represent the company. Uh so first I'm
going to go through sorry why rapid
diagnostics are needed especially in the
field of infectious diseases and AMR. So
in uh his review on antimicrobial
resistance in 2016, Lord Jim O'Neil
actually um identify rapid diagnostics
as one of the 10 key solution to tackle
AMR. So why? Because rapid diagnostic
have the potential to identify if a
disease is due to a bacteria or a virus,
what type of bacteria it is, and if it's
resistant to some treatment. So
therefore the rapid molecular diagnostic
will have the potential to help prevent
infectious disease spread, facilitate
appropriate selection of treatment,
tackle antimicrobial resistance and
reduce test testing time and in most
cases also testing costs as well as cost
to infrastructures health system.
So what are the current diagnostic
methods for MR? So they are in two main
categories. The first one is phenotypic
culture based method. So it tests the
growth or non-growth of the organism in
presence of antibiotics.
It encompasses disk diffusion, gross
micro dilution and gradient diffusion
for example. The time to results is
usually two to three working days from
isolated bacteria. So from the sample
it's three to five days and there are
now some microfidics and optical method
that can help speed up the process like
we just saw um to six to 24 hours or
even uh quicker. So in less than a day
you can have a a result. The second
category is genotypic and molecular
method. So it's based on the detection
of nonresistance gene or mutation
directly from a sample. It had in
includes PCR and qPCR but also w genome
sequencing and metagenomics and the time
to results is one to two hours for PCR
and 24 to 48 hours for sequencing. So
what we offer in vida is in this
molecular um diagnostics of AMA or
infection related.
So we offer innovative AI lamp
platforms. So Lamb stands for loop
mediated isotamal amplification
and so our devices um are portable and
low cost and it goes with matching
consumable and matching test. The end to
end uh testing the wall process is from
sample collection to test result in less
than an hour. So it's between 30 minutes
and 45 minutes depending on the test.
It's it it enables accurate testing
where it's needed most um like pensite
or a point of care.
So this is um the product suit that we
have. So we have se rapid sample
preparation devices called the vread
that allows sample preparation in less
than six minutes. So it's the piped that
you can see at the top on on the right here.
here.
We then have AI lamp devices that will
perform the wool amplification but also
monitor the amplification of the target
and it has embedded AI that will analyze
the results and output the results on
the device and also on an smartphone
application that is connected to the device.
device.
It works with um bispoke reagent. So we
have our own um lamp master mix that
works with the the VH6 device for
enhance performance. And as I was
saying, it's connected to a smartphone
but also to a cloud and that allows data centralization.
centralization.
All of those hardware and consumables
are um can be tailored to diver diverse
end user needs and there are three IVD35
and MH approved.
So those here are a few application that
we currently have mostly with the
university of sorry. So we have a lamp
assay that has been uh fully validated
and commercialized. It obtained very
high sensitivity and specificity when
compared to qPCR and it obtain CTDA approval.
approval.
We also have some tuberculosis lambes to
identify the different species of
bacteria involved in tuberculosis test
tuberculosis disease and that was
developed with the university of sorry
and has been validated with um
university in Ghana.
We also have um aspigulous species
diagnostics. This is in collaboration
with the University of Surrey and with
Cinois. And finally we developed some
cleilony and carbopene detection test in
collaboration with the university of
sorry. So here we really we have um
rapid testing solution that can inform
treatment from the sample in under one
hour and because it's highly portable it
can be performed point of care and it
can be used in combination with um gold
standard test or phenotypic test.
So we are always looking for partners.
So if you interested please contact us.
Um and if you have any question please ask.
>> Thank you.
farm environment or perhaps in an
environment in a lower middle income
country. Do you see any problems there
either in terms of the preparation of
the samples or indeed of the operation
of the of the hardware to to get your
test result?
>> So we are really focusing to have those
type of of platform that can be used in
those conditions. So the only thing you
will need is um part of a table that is
relatively clean and the sample
preparation can be done with um our vual
device that does it quickly and then you
can use the eye lamp straight away that
it would just need like a little table
really. That's that's the main point of
all of the the devices that we are um
developing to be performed decentralized
>> and and this is competitively priced as well.
well.
>> It's a lot cheaper than >> QPCR.
>> QPCR.
>> Um it would be more expensive than
lateral flow but then it's a lot more
sensitive as well and gives a lot more information.
information. >> Yeah.
>> Yeah.
>> So yeah, that's
>> any other questions. Okay.
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