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Hey everyone, it's nurse Sarah and in
this video I want to do a quick review
over the antibiotic class glyopeptides.
So let's get started. The glyopeptide
class actually doesn't have a common
prefix or suffix and a popular
medication in this class is vancoyasin.
Now whenever you look at this medication
don't get confused and think it's an
aminoglycide because remember that class
tends to end in mison like mycin n or m
i cin. However, this is not it. Look
more at this name a little bit. Look at
that co in there. Where else have you
seen co at? In its main class name,
glyco. So this is a glycoeptide.
Now what does it target? It targets gram
positive like MRSA and cedith. So what's
it going to treat? It's going to treat
those two along with bone infections,
pneumonia and endocarditis. So how does
it do this? Well, it works to inhibit
bacterial cell wall synthesis. So it has
a bacterial codle effect. Now to help
you remember the important concepts
about this class particularly
venkcomyosin I want you to remember the
word vanco. Venkcomiaosin is very toxic.
It has a narrow therapeutic range. So we
are going to draw trough levels. See
where our patients at. And you want to
draw the trough before the fourth dose
with a goal of it being about 10 to 20
micrograms per milliliter. Also, you
want to administer this very slowly IV
over more than 60 minutes because we
want to prevent a non-allergic reaction
and this is where the patient will start
to have flushing, rash, and hypotension.
It's also nephrotoxic. So, it can hurt
the kidneys. You want to monitor BUN and
creatin. Now, when VancO is being used
to treat CEDIFF, you want to remember
that you're going to be giving them the
oral form of this because that
medication is going to go in the GI
tract, which is where our bug is hanging
out. the IV form doesn't really treat
it. And then lastly, O for otoxicity.
It can harm the hearing. So monitor the
patient for ringing in the ears, hearing
loss, and vertigo. Okay, so that wraps
up this review. And if you'd like to
watch more videos in this series, you
can access the link in the description below.
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