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Chapter 1 Recorded Lecture
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Hi Everyone. Welcome to anatomy and
physiology. In this first chapter, An
Introduction to the Human Body, we are
going to look at and examine some
anatomical terms, anatomical structures,
we are going to examine some prefixes, and
we are also going to examine the
structural organization of the human
body. So we're going to talk a little bit
about the eleven organ systems that you
will be studying throughout the anatomy
and physiology courses of Anatomy 1 and
Anatomy 2. So let's take a look and see
what Anatomy means. Anatomy is the study
of the structure of body parts and the
relationships to one another. That's
going to be different from physiology,
which we'll get to in a second, which is
the study of the function of those body
parts. So when we look at the form or
structure, we can divide anatomy into
what we call gross or microscopic
anatomy. Gross anatomy is the study of
structures large enough to be seen with
the naked eye. Microscopic, which can be
further subdivided into cytology and
histology, is a study of structures that
are too small to be seen with the naked
eye. And when you get into lab you will
study histology in more detail. So here
is an example of gross anatomy where we
could look at large structures such as
the brain. We could also examine the
heart the stomach as other examples.
Microscopic we can't see with the naked
eye so we generally use a microscope and
in lab you'll be using a compound
microscope to study certain histological
structures like different forms of
epithelial tissue or connective tissue.
In this example, we're looking at a
neuron and you can see the neuron cells
and we can even see the little dark spot
in the center of the cell which is the
nucleus. You'll be examining various
organelles of the cell later on. So gross
anatomy we can even further subdivide
into regional, surface, or systemic
anatomy. Surface anatomy is the study
of internal structures as they relate to
the overlying skin surface. Regional
anatomy considers the regions of the
body like the head and the extremities
and all the systems in a particular
region. We will be studying different
regions of the body like the abdominal
pelvic region which looks at the
abdominal organs and the pelvic organs
or the thoracic region which encompasses
the lungs. Systemic anatomy gives
attention to all the structures of a
particular system in the body regardless
of location. Microscopic anatomy, again
micro means small, so we're concerned
here with structures that are too small
to be seen with the naked eye. Now
there's different types of microscopes
that we can use to study these
structures again in our lab, we will be
using the compound light microscope but
there are also dissecting microscopes that you
may use in other courses. The
electron microscope, which allows us to
see even further detail.
Now within microscopic anatomy, cytology
is the study of individual cells (cyto = cells)
and histology (histo means tissues) so
we're looking at the study of tissues
and their functions. Physiology is the
study of function and physiology has
various there's several topics most of
which consider the function of specific
organ systems. Physiology often focuses
on events that are going on either
within the cell or even at a molecular level.
So there is cell physiology, for example
immunology, renal physiology, and cardio
vascular physiology. And those are just a
few examples of the subdivisions of
different organ systems. So renal, we would
look at the kidneys for example.
Cardiovascular, we would study the
operation of the heart and blood vessels.
Now the basic principles of cell theory
are that 1) cells are the building blocks
and that includes all plants and animals;
2) cells are produced by the division of
pre-existing cells through mitotic
division for example and 3) cells are the
smallest structural units that perform
all vital functions. We will examine
the cell in more detail. The cellular
level is the smallest unit of life and
it varies widely in size and shape
according to the cells function. Now if
we look at the different levels of
organization we can see that we have the
molecular level and for example, hydrogen
and oxygen atoms. So atoms they are the
building blocks of matter. Now they can
combine to form molecules.
Molecules combine in specific ways to
form organelles which are the basic unit
of living cells. So at the cellular level,
we can examine for example interactions
between molecules and compounds that
form the organelles of cells. Cells again
they are the structural building block
of all plants and animals. And then we
have the tissue level. Tissues are groups
of similar cells. A tissue level is a
group of cells that have a common
function. So these are cells that work
together to perform one or more specific
functions. Examples would be muscle
tissue, nerve tissue, connective tissue, or
even epithelial tissue. Next, we have the
organ level. So organs contain two or
more types of tissues. The organ level is
made up of discrete structures that are
composed of at least two groups of
specific function in the body. Then we
tissues that work together to perform a
have the organ system. These are organs
that work closely together. The organ
system level is a group of organs that
work closely together to accomplish a
specific purpose. The types of tissues
that comprise organs and organ systems
perform vital functions of the body.
Then finally we have all organ systems, the highest level
This is the total of
all structures working together to
promote homeostasis in the body. And we
will be examining
different organ systems. So here's some
examples of organ systems that we will
study throughout your course in anatomy
one and in anatomy two: 1) the lymphatic
system. The lymphatic system is composed
of lymph nodes, spleen, thymus gland, bone
marrow, and tonsils. It also houses the
immune system cells of the body, provides
protection against infection and disease,
transports tissue fluid called lymph, and
absorbs fats.
2) The respiratory system is also shown
here and it's composed of the lungs,
trachea, larynx, and nasal passages.
This is where we have the exchange of
respiratory gases like oxygen and carbon
dioxide between the air and circulating
blood. 3) The muscular system is composed of
muscles attached to the skeleton which
provide locomotion, support, and body heat
production. 4) The nervous system is
composed of the brain, spinal cord, and
peripheral nerves. The nervous system
is one of our two communication systems
of the body with the endocrine system being
the other. The nervous system directs
immediate responses to stimuli
usually by coordinating the activities
of other organ systems. 5) The integumentary
system is composed of the skin, hair, and
nails. It provides external support and
protection of the body and also is
involved in temperature regulation. 6) The
skeletal system is composed of bones and
it provides internal support and a
flexible framework for body movement. In
addition, it forms blood cells and stores
minerals. 7) The endocrine system is
composed of hormone secreting glands
like your thyroid gland, pituitary gland,
adrenal gland, pancreas, pineal and others.
The endocrine system functions to
secrete hormones that direct long-term
changes in the activities of other organ
systems. 8) The cardiovascular system
is composed of the
blood, heart, and blood vessels. It
provides internal transport of nutrients
and oxygen to body cells while also
removing wastes and carbon dioxide being
transported away from body cells. 9) The
digestive system is composed of the
salivary glands, esophagus, stomach, small
intestine, large intestine, liver, and
gallbladder. The digestive system is
involved in taking in nutrients, breaking
them down, and allowing for the
absorption of food in order for the
cells of the body to acquire nutrients,
minerals, vitamins, and water while also
eliminating waste products in the form
of fecal material. 10) The urinary system is
composed of the kidneys, ureters, urinary
bladder, and urethra. The urinary system
filters the blood to remove nitrogenous
waste products, eliminate excess water,
salts, and waste products, while also
controlling pH and electrolyte balance
of the body. 11) The reproductive system we
have both the male and female.
Female reproductive system which is composed of
ovaries, the uterus,
vagina, and mammary glands in the female
and in the male you have the testes,
scrotum, prostate gland, seminal vesicles,
and penis. The reproductive system is
involved in the production of sperm and
egg as well as the secretion of sex
hormones and copulation. So these are the
organ systems of the body and you need
to be sure that you can identify the
major organs of each of the 11 organ
systems and also be sure you can
identify the major functions of each of
the 11 organ systems that we just went
over.
remember the cells of the body depend on
the organ systems to meet their survival
needs and the organ systems of the body
work cooperatively to perform necessary
life functions and there is a couple of
tables listed here which gives you some
information and characteristics of
living organisms so a living organism is
able to respond it means it has the
ability to sense and detect both
internal and external stimuli and to
generate a response appropriate to that
stimulus that's required in order for an
organism to adapt be able to change
their behavior modify provide
capabilities or structure because we're
constantly in a changing environment and
so we have to be able to adapt for
example to different changes in
temperature may be different changes in
oxygen level if we travel to higher
altitudes so those are a couple of
examples growth and development
we have to be able to increase in cell
size in size and cell number so we have
patterns for growth and development
reproduction we have to be able to
reproduce in order to produce the next
generation we have to be able to move
about so we have to distribute materials
throughout large organisms be able to
change our position or orientation even
a plant has to do that maybe to get more
sunlight or the roots to grow in order
to have access to water animals we have
to be able to move around respiration we
have to be able to take in oxygen
distribute it to our cells and get rid
of the metabolic waste product from
breathing which is carbon dioxide
now the other requirement or
characteristic of living organisms
circulation is the movement of fluid so
we transport fluids within the organism
and within the human body that involves
the cardiovascular system which is our
heart as the pump and we have a network
of blood vessels digestion the breakdown
of ingested foodstuffs in very simple
molecules that can be easily used for
chemical reactions in the body and be
absorbed across cell boundaries
excretion we have to be able to remove
chemical waste products that are a
natural part of the multitude of
metabolic processes that occur within
the human body so here's an example
marathon
they demonstrate two characteristics of
living or humans or organisms they can
respond and move there is anatomical
structures and physiological processes
in place that allow runners to
coordinate actions of muscle groups and
also sweat in response to rising
internal body temperature which allows
the body to cool metabolism so metabolic
processes are constantly occurring in
the body and there is a series of
reactions anabolic reactions those are
reactions that build things and
catabolic reactions which break
materials down and release energy
metabolism includes both anabolic and
catabolic reactions catabolic reactions
again they release energy so when we
take in food for example we break that
food down into smaller and smaller
components so that the body can absorb
those nutrients we release energy in the
process if we want to build things
within the body like hormones that's an
anabolic process and that requires
energy input
now the requirements for human life are
we need oxygen nutrients a narrow range
of temperatures and atmospheric pressure
oxygen oxygen is only a small percentage
of atmospheric air about 20% but that
oxygen is a key component of the
chemical reactions within our bodies
that help keep us alive and this
includes reactions that you will study
later on that produce ATP
nutrients substances in our food in our
beverages that are essential to human
survival the three basic classes of
nutrients are water the energy building
are yielding nutrients carbohydrates and
lipids and body building nutrients
proteins and the micronutrients vitamins
and minerals we also need a narrow range
of temperature so the body can respond
to short-term changes in body
temperature for example as you just saw
sweating went to hot or shivering when
it's too cold when body temperatures
rise well above or drop well below those
normal levels certain proteins or
enzymes that may facilitate chemical
reactions might lose their normal
structure and their ability to function
and the chemical reactions of metabolism
cannot proceed we also need a stable
atmospheric pressure atmospheric
pressure is the pressure that's exerted
by the mixture of gases which are
primarily nitrogen and oxygen in the
Earth's atmosphere although you may not
perceive it readily atmospheric pressure
is constantly pressing down on your body
this pressure keeps gases within your
body dissolved in your blood plasma your
ability to breathe take in oxygen and
release carbon dioxide also depends on a
precise atmospheric pressure and you
will study this in further detail in
anp2 when you discuss the respiratory
system so some examples of these
requirements for human life are shown
here harsh conditions like at a high
altitude found on Mount Everest climbers
to accommodate extremes in temperature
low oxygen levels low barometric
pressure so the body has to adapt or
they must have resources in place in
order to survive in those conditions
extreme temperatures
humans can adapt to some degree to
repeated exposure to high temperatures
but the temperature again cannot get too
high or it can damage certain proteins
or enzymes within the body and all of
this is important to homeostasis
homeostasis is the ability of the body
to maintain a relatively constant
internal environment regardless of
environmental changes it involves
continuous monitoring and regulation of
many factors or variables which include
for example both volume of fluid
composition of chemicals in our in our
fluid and we have systems in place that
measure and monitor homeostasis so we
have to maintain homeostasis this
steady-state environment a balance or
equilibrium where our internal
conditions remain relatively constant
despite changes in external conditions
this is vital to an organisms survival
failure to maintain homeostasis results
in illness disease and can even result
in death homeostatic control is not
precise it maintains a normal range
rather than an absolute value or
setpoint and an example of this can be
seen within our blood pH our blood pH
ranges between seven point three five
and seven point four five now the
setpoint is seven point four but it can
vary
little bit on either side of that now
homeostatic regulation involves feedback
mechanisms that consist of two three
components a receptor a control center
and an effector now let's look at
example of this so the receptor is also
known as the sensor it detects changes
in either the internal or external
environment or stimulus the control
center receives and processes that
information supplied by the receptor and
sends out a command and that command
goes to the effector which responds to
the commands by opposing the stimulus
this is an example of a negative
feedback loop which provides stability
and is the main way the body maintains
homeostasis so an example of that is
provided here body temperature it
exceeds 37 degrees Celsius your nerve
cells in your skin in your brain sense
this that information is sent to your
temperature regulatory Center in your
brain which sends out signals to your
sweat glands throughout the body to
perspire which cools the body as the
sweat evaporates now homeostasis is not
precise there is some oscillation around
the setpoint and that is pretty much a
characteristic of homeostatic control
mechanisms now another type of feedback
mechanism that you should be familiar
with is positive feedback negative
feedback as you saw goes in the opposite
direction of the
change positive feedback mechanisms
enhance or exaggerate the original
stimulus so it causes sometimes a
cascade or amplification effect and it
accelerates a process generally to
completion so it intensifies or enhances
the original stimuli an example is shown
here with childbirth labor contractions
so the brain stimulates the pituitary
gland to secrete oxytocin a hormone
oxytocin goes via the blood stream to
the uterus it stimulates uterine
contractions and pushes the baby towards
a cervix as this process continues the
head of the baby pushes against the
cervix and then the nerve impulses from
the cervix is transmitted to the brain
so once the baby is born the stimulus is
removed and the process is shut off
positive feedback mechanisms typically
activate events that are again
self-perpetuating
most positive feedback mechanisms are
not related to the maintenance of
homeostasis in the body blood clotting
is another example and homeostatic
mechanisms are generally maintained
through negative feedback now anatomical
terms there is some anatomical terms
that you must be familiar with and there
is a series of tables that are presented
here which will demonstrate various
anatomical terminology so we have to
know these anatomical terms roots
prefixes suffixes you're even going to
have to learn regional terms that
indicate location
in the body directional terms that are
used for points of reference and so on
so Anatomy uses a special language it
does have an origin in Latin and Greek
which is named after the discovery and
knowing these terms will help you
throughout your study in this course so
word roots prefixes and suffixes are
listed here for you make sure you know
all of these roots prefixes and suffixes
so for example cardio means heart endo
within chemo blood this will help you
later on
Myo muscle and then you've got different
regions of the human body now one thing
to note in this picture is the
anatomical position is being
demonstrated so to further increase
precision anatomist standardized the way
in which they view the body so just like
a map is normally orientated with north
at the top the standard body map or
anatomical position is that of the body
standing upright with the feet at
shoulder width and parallel toes facing
forward the upper limbs are held out to
each side and the palms of the hands
face forward a body that is lying down
is described as either prone or supine
prone describes a face down orientation
supine describes a face up orientation
so there's various regions of the human
body and they are used to indicate
locations on or in the body like
the abdominal region anterior torso
below the diaphragm the brachial is the
arm axillary is the armpit buccal is
cheek coxal hip so you have to know all
of these regional terms that indicate
locations on or in the body you also
have to be familiar with directional
terms and sectional terms that describe
specific points of reference on the body
so anterior or ventral is toward or at
the front of the body posterior area or
dorsal is toward or at the back of the
body superior or cranial is above toward
the head end or upper part of the
structure or body inferior or caudal is
below away from the head end or toward
the lower part of the structure or body
medial toward or at the longitudinal
axis of the body towards the midline
lateral away from the longitudinal axis
away from the body
proximal closer to the origin of the
body part or the point of attachment of
a limb to the body trunk distal farther
from the origin of a body part or the
point of attachment and then we have
superficial or external toward or at the
body surface and deep or internal away
from the body surface more internal we
also have various sectional planes a
sagittal plane is a vertical plane that
divides the body into right and left
parts now we can have a midsagittal
plane which divides the body exactly in
the midline parasagittal are all other
sagittal planes that are offset from the
midline frontal or coronal any plane
dividing the body into an anterior and
posterior portion and a transverse or
horizontal is a plane dividing the body
into superior and inferior portions not
shown here is an oblique which is a cut
that's made diagonally between a
horizontal and a vertical plane in
addition you have to learn body cavities
body cavities protect internal organs
from shock or impact and allow them to
change shape so you have the dorsal body
cavity which is composed of two smaller
cavities the cranial cavity and the
vertebral cavity the cranial cavity
contains the brain the vertebral cavity
contains the spinal cord the ventral
body cavity also known as the coelom
houses internal organs of the body and
those are collectively generally
referred to as the viscera or guts you
have the thoracic cavity which contains
the pleural cavity the right and left
contains the lungs and the mediastinum
is the space between the pleural
cavities containing the thymus lymph
vessels esophagus trachea and nerves now
you see they have the abdominal cavity
and the pelvic cavity this is sometimes
also referred to as the abdominal pelvic
cavity the abdominal cavity contains
digestive organs the pelvic cavity
contains the bladder
reproductive organs and rectum the
dorsal and ventral body cavities are
shown here again the ventral body cavity
however includes membranes ventral body
cavities are lined with serous membranes
all serous membranes are double layered
the outer layer is the parietal layer
which is the layer that's more towards
the body wall while the inner layer is
called the visceral more towards the
organs and between the parietal and
visceral layers is a watery lubricating
fluid called serous fluid and you'll be
studying serous membranes throughout the
course so here's some tables again they
give you the regions of the human body
some of the areas you have to know and
in the abdominal pelvic region we can
also divide this into quadrants and
regions so the abdominal pelvic
quadrants you have the right upper
quadrant which contains the liver the
left upper quadrant contains the stomach
and spleen the left lower quadrant
contains the descending colon and the
right lower quadrant contains the cecum
and ascending colon and so that would be
this blue line here which is dividing it
into four quadrants the red lines are
dividing the abdominal pelvic into
regions you should know the quadrants
and regions and the organs contained
within the umbilical region is the
centermost region
deep to and surrounding the navel the
epigastric is superior to the umbilical
region the hypogastric is located
inferior to the umbilical region the
right and left hypochondriac flanks the
epigastric region laterally the right
and left lumbar lies lateral to the
umbilical region and the right and left
iliac or in Guino
is lateral to the hypogastric region and
you've got some pictures here that show
those different regions that I just went
through
so there's your different abdominal
pelvic regions here is the serous
membranes that I refer to so again
visceral more toward the organ parietal
lining the body wall the example shown
here is the heart where you've got the
parietal pericardium which lines the
perio cardial cavity and you can see the
visceral pericardium
so serous membranes again they usually
are their double layered and between the
visceral and the parietal is that
lubricating fluid called serous fluid
now there's many different ways that we
can take images of the human body
without actually having to go through an
invasive procedure so different types of
medical imaging that can be used or
x-ray machines CT machines MRI machines
pet machines or ultra sonography and
you're going to see some examples of
those next so an x-ray
is a high-energy electromagnetic
radiation which allows us to see
internal structures of the body like our
bones so if you've ever broken a bone or
has suspected breaking a bone you may
have had an x-ray taken other types of
medical imaging or shown here so a CT
scan in this top portion here shows
different areas of the head and these
are transverse sections an MRI machine
uses a magnetic fields PET scans are
another way to create images and they
can show active blood flow or the
activity of an organ that they're
examining ultrasound technology is quite
often used to monitor pregnancies
because it's the least invasive imaging
technique and there is no
electromagnetic radiation therefore it's
not harmful to the developing fetus this
concludes chapter one an introduction to
anatomy and physiology
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