The core theme describes the crucial role of eukaryotic release factors (eRF1 and eRF3) in terminating protein synthesis by recognizing stop codons on ribosomes and facilitating the release of the newly synthesized polypeptide chain.
Mind Map
클릭해서 펼치기
클릭해서 인터랙티브 마인드맵 전체 보기
in the cytosol of an
eukaryotic cell two types of erf
are present they are erf1
and erf3
the erf stands for eukaryotic release factor
factor
the erf3 is a gtp binding protein
when a ats ribosome having a newly formed
formed
completed protein chain reaches a stop codon
codon
like uaa or
uga or uag
the erf1 along with erf3 dot
gtp enters the ribosomal complex
probably at or near the a side
and the erf1 recognize this top corner
directly the other name
of erf3.gtp
is erf3 gt ph
the recognition of stop codon by erf-1
leads to erf3 bound gtp
hydrolysis to produce a gdp
and a pi here the hydrolysis step
acts as a proof reading step
because it ensures that the previous step
step
means the recognition of a stop codon
by erf 1 has occurred correctly
and then only it allows subsequent step
or further steps to proceed after the
ensurement given by the hydrolysis
that the erf1 has correctly recognized
a stop codon the peptidyl trna
present in the p site of a ribosomal complex
complex
is added with a h2o molecule
in presence of peptidyl transferase
due to this addition reaction the newly
formed completed protein chain
separates from the trna and
released into the cytosol then
additional release factors promote
the dissociation of ats ribosome
as a result the 40s and
60s ribosomal subunits mrna
trnas erf1
dot gdp are freed to carry out
please like subscribe and share you
텍스트나 타임스탬프를 클릭하면 동영상의 해당 장면으로 바로 이동합니다
공유:
대부분의 자막은 5초 이내에 준비됩니다
원클릭 복사125개 이상의 언어내용 검색타임스탬프로 이동
YouTube URL 붙여넣기
YouTube 동영상 링크를 입력하면 전체 자막을 가져옵니다
자막 추출 양식
대부분의 자막은 5초 이내에 준비됩니다
Chrome 확장 프로그램 설치
YouTube를 떠나지 않고 자막을 즉시 가져오세요. Chrome 확장 프로그램을 설치하면 동영상 시청 페이지에서 바로 자막에 원클릭으로 접근할 수 있습니다.
