Osteogenesis (OIFC) is the fundamental biological process by which bone tissue is formed, either by replacing connective tissue or cartilage, essential for skeletal development, growth, remodeling, and repair throughout life.
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bone formation also known as
osteogenesis or oifc is the process by
which bone tissue replaces embryonic
connective tissue to form the skeleton
from childhood to early adulthood oifc
lengthens and thickens bone in addition
the process of oifc is used throughout
life to remodel
bones there are two methods of prenatal
matrix over a few days osteoblasts
become osteocytes and calcium and other
mineral salts are laid down hardening The
The
Matrix the bone matrix develops thin
Columns of bone called tabuli which fuse
blood and lymphatic vessels grow into
the surfaces of the newly formed bone
and develop red bone
marrow outside of the bone a dense layer
of connective tissue called the periostium
periostium
forms most outer layers of spongy bone
are eventually replaced by compact bone
osificante providing the brain with greater
protection endochondral oifc the
replacement of cartilage by bone occurs
skeleton the process begins when
embryonic mezen Kim condenses forming
the cartilage model the shape of the
the model grows within the fetus
lengthwise growth is attained via
interstitial growth width is attained
growth a nutrient artery penetrates the
perichondrium increasing nutrient
availability to the
cells osteogenic cells are stimulated to
differentiate into
osteoblasts these cells secrete Matrix
beneath the parond
that forms a thin shell of compact bone
known as the bone
collar as the parond begins to form bone
it is now called the
periostium the bone collar reduces
diffusion to the cartilage inside the
model depriving it of
nutrients capillaries grow into the
disintegrating cartilage delivering
osteoblasts the new growth forms a primary
primary
osificante tissue will replace most of the
cartilage osteoblasts deposit bone
remodeled the cavity fills with
marrow oifc proceed forming the main
diaphysis around the time of birth blood
vessels enter the epiphyses the ends of
as a result the interior of the
epiphysis remains
spongy secondary oifc leaves a thin
layer of hyolin cartilage covering the
epiphyses this is known as articular
cartilage and it reduces the friction
and shock in bone joints the change to
the epiphysis also forms the epiphysial
plate a l of highin cartilage that
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